pentobarbital will reduce the level or impact of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

Keep track of Intently (1)pentobarbital will boost the amount or result of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs.

pentobarbital will lower the level or result of losartan by influencing hepatic enzyme CYP2C9/10 metabolism. Minimal/Significance Not known.

benzhydrocodone/acetaminophen and pentobarbital both maximize sedation. Keep away from or Use Alternate Drug. Limit use to clients for whom substitute procedure selections are inadequate

pentobarbital will lessen the level or result of darunavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs.

pentobarbital will reduce the level or effect of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Potent CYP3A4 inducers may perhaps minimize suvorexant efficacy; if amplified suvorexant dose demanded, never exceed twenty mg/working day

pentobarbital will lower the level or effect of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.

Barbiturates can result in fetal harm when administered to your Expecting woman; retrospective, situation-controlled scientific tests have suggested a connection amongst maternal use of barbiturates and the next-than-expected incidence of fetal abnormalities

Keep an eye on Closely (one)pentobarbital will check here reduce the extent or result of hydrocodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Warning when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone may raise and can lead to likely deadly respiratory depressionSerious - Use Choice (1)hydrocodone, pentobarbital.

buprenorphine subdermal implant and pentobarbital equally raise sedation. Avoid or Use Alternate Drug. Limit use to patients for whom option treatment method selections are insufficient

Far too quick administration could trigger respiratory despair, laryngospasm, apnea, or vasodilation with slide in blood pressure level

pentobarbital will decrease the extent or influence of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. CYP3A4 inducers haven't been analyzed, coadministration not advisable by producer